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| 產(chǎn)品參數(shù) | |||
|---|---|---|---|
| 品牌 | 菲恩生物 | ||
| 適用范圍 | 僅供科研使用 | ||
| 規(guī)格 | 100μg | ||
| 加工定制 | 否 | ||
| 驗證應(yīng)用 | ELISA | ||
| WB | |||
| 宿主 | 兔 | ||
| 適應(yīng)種屬 | 人源，大鼠，小鼠 | ||
| 可售賣地 | 全國 | ||
| 材質(zhì) | 液體 | ||
名稱：抗KLHL22抗體(anti-KLHL22 antibody)
貨號：FNab04620
適應(yīng)種屬：人源，大鼠，小鼠
規(guī)格：100ug(微克)
狀態(tài)：液體
純化方法：免疫親和純化
純度：經(jīng)sds-page分析，純度大于95
宿主：兔
亞型：igg
存儲：用添加了0.02疊氮化鈉和50甘油的pbs溶解，ph值7.3，可在-20℃下保存12個月（避免反復(fù)凍融）
免疫原：kelch-like 22(Drosophila)
分子量：72 kDa
驗證應(yīng)用：ELISA, WB
建議稀釋比例：WB: 1:500-1:2000
克隆性：多克隆
uniprot id：Q53GT1
背景介紹：Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint(SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation。
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04620(KLHL22 antibody) at dilution of 1:3000。
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